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Other various tests for diabetes

Here are a few other tests (by far not all of them) that are important in either the diagnosis of diabetes, or if you have diabetes they are good to have to keep tabs on things.

Random glucose test – This is usually a fingerprick, or done while draining your arm/body of blood for other tests.  They test the amount of glucose (sugar) in your blood at the given moment.  Two random tests above 200 mg/dl is a diagnosis for diabetes.  That is kind of tricky for us with CFRD since illness is common and so is steroid use, which will give you higher than usual blood glucose levels.

C-Peptide test – I was told there is no real ability to measure the amount of insulin your body produces.  But when your body produces insulin it also produces a protein, c-peptide.  In theory if your body does not make enough insulin, you won’t make much c-peptide either.  Usually this means that your pancreas has given up the ghost and is no longer working properly.  I had this test done, as required to get insurance coverage (my crappy old policy) for my insulin pump.  Welllll… I failed the test… or did I pass it?? Turns out that my body makes enough c-peptide to qualify me as “normal” and not needing insulin.  Well… that is by far, not true.  The exact cause of CFRD is truely unknown to this date.  Of course our lil pancreases are on their way to complete self-distruction (which mine showed via a CT scan), but there is a study out there that claims the creation or use or something about the natural made insulin doesn’t work correctly.  Which is why I apparently have insulin dependent diabetes, but still have a normal amount of c-peptide (or at least I did last year).

Antibody test -  This is where Type 1 diabetics differ from all other types and exactly why CFRD is NOT Type 1 (although treatment is similar which is not to be confused with cause).  Type 1 diabetes is an autoimmune disease which is caused by antibodies that attack the insulin producing cells, the beta cells, in the pancreas.  If you have diabetes and have antibodies, you have Type 1.  If you have diabetes and do not have antibodies, you have a Type Other than Type 1.  A cure for “Type 1″ diabetes will not cure my diabetes and that is why I am such an advocate for the “Type Other”s.  It is possible for someone with CF to have Type 1, it is the same rate as for the “normal” population, but just because you have cystic fibrosis related diabetes and you are insulin dependent, this does not make you Type 1.

Urine Sugar tests – If you have too much sugar in your blood, it will spill over in your kidneys (which is not good) into your urine.  Usually one of the first tests they do when they suspect diabetes.

Liver function tests – For folks with CF our livers are at risk of damage from all the drug coctails we are required to take.  I am only mentioning this test because I know a few CF docs who try putting their CFRD patients on pills for treatment instead of insulin shots.  I guess pills are ok, but I would be hesitant because most diabetes pills have a high risk of causing liver issues…. Just one more thing I do not want to add to my list of things I need to deal with.

I am sure there are plenty of other tests I am not noting in this post.  Anyone else want to chime in? :)

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3 Comments so far (Add 1 more)

  1. I really enjoyed your last 3 posts and learned a lot. I appreciate the science behind the disease.

    1. Amanda on February 20th, 2009 at 4:59 pm
  2. Hi Laurie, thanks for your comment. The true cause of CFRD still hasn’t been found. Here’s one article back from 2006 that describes one other facet of what they believe one of the causes is:
    http://www.medicalnewstoday.com/articles/46755.php

    I also read another article today about CF related inflammation and Beta-cell injury, as a cause of CFRD.

    Looks like they are still trying to figure it out. I think it is just easier for some docs to describe it as your doc has said to you. If what your doc said was right, many of us with CFRD would not have normal C-Peptide tests (which a lot of us do).

    2. Salty on February 20th, 2009 at 3:02 pm
  3. I was told that because our bodies produce so much mucous that this is what affects the pancreas from producing the correct amount of insulin; because the mucous clogs our ducts. That’s why we have so mnay organ problems. Liver, Pancreas, Intestinal etc. That was the explaination my Drs. gave me for my diabetes.

    3. Laurie on February 20th, 2009 at 6:31 am

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